A-58365B

Names

[ Name ]:
A-58365B

[Synonym ]:
4-Carboxy-1,3,4,6-tetrahydro-9-hydroxy-6-oxo-2H-quinolizine-7-propanoic acid
2H-Quinolizine-7-propanoic acid,4-carboxy-1,3,4,6-tetrahydro-9-hydroxy-6-oxo

Biological Activity

[Description]:

A-58365B is an Angiotensin-converting Enzyme (ACE) inhibitor. A-58365B has antihypertensive effects[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[References]

[1]. Walter M. Nakatsukasa, et al. Process for enzyme inhibitor. Patent. US4404282A

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Boiling Point ]:
608.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₅NO₆

[ Molecular Weight ]:
281.26100

[ Flash Point ]:
321.7ºC

[ Exact Mass ]:
281.09000

[ PSA ]:
116.83000

[ LogP ]:
0.53310

[ Index of Refraction ]:
1.644

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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