PSNCBAM-1

Names

[ Name ]:
PSNCBAM-1

[Synonym ]:
PSNCBAM 1
1-(4-Chlorophenyl)-3-[3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl]urea

Biological Activity

[Description]:

PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[Target]

hCB1-R:0.1 μM (EC50)

[References]

[1]. Horswill JG, et al. PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats. Br J Pharmacol. 2007 Nov;152(5):805-14.

Chemical & Physical Properties

[ Boiling Point ]:
521.5±50.0 °C(Predicted)

[ Molecular Formula ]:
C₂₂H₂₁ClN₄O

[ Molecular Weight ]:
392.88100

[ Exact Mass ]:
392.14000

[ PSA ]:
57.26000

[ LogP ]:
5.85720

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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