DMT-2'-O-TBDMS-1-methylpeudouridinePhosphoramidite

Names

[ Name ]:
DMT-2'-O-TBDMS-1-methylpeudouridinePhosphoramidite

Biological Activity

[Description]:

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₆₃N₄O₉PSi

[ Molecular Weight ]:
875.07

[ Storage condition ]:
-20°C

Related Compounds

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