AZD-1092
Names
[ CAS No. ]:
871656-65-4
[ Name ]:
AZD-1092
Biological Activity
[Description]:
AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes.
[References]
References 1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35. 2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779 View Related Products by Target Glucokinase
Chemical & Physical Properties
[ Molecular Formula ]:
C24H26N4O5
[ Molecular Weight ]:
450.495