Boc-Val-Cit-OH

Names

[ Name ]:
Boc-Val-Cit-OH

[Synonym ]:
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-valyl-N5-carbamoyl-L-ornithine
MFCD22381207
L-Ornithine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-

Biological Activity

[Description]:

Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
624.8±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₃₀N₄O₆

[ Molecular Weight ]:
374.433

[ Flash Point ]:
331.7±31.5 °C

[ Exact Mass ]:
374.216522

[ LogP ]:
0.66

[ Vapour Pressure ]:
0.0±3.9 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Storage condition ]:
2-8°C

Boc-Val-Cit-OH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds