870487-08-4

870487-08-4 structure
870487-08-4 structure
  • Name: Boc-Val-Cit-OH
  • Chemical Name: Boc-Val-Cit-OH
  • CAS Number: 870487-08-4
  • Molecular Formula: C16H30N4O6
  • Molecular Weight: 374.433
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2019-09-11 10:03:03
  • Modify Date: 2024-01-02 17:18:08
  • Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name Boc-Val-Cit-OH
Synonyms N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-valyl-N5-carbamoyl-L-ornithine
MFCD22381207
L-Ornithine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-
Description Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1.

Density 1.2±0.1 g/cm3
Boiling Point 624.8±55.0 °C at 760 mmHg
Molecular Formula C16H30N4O6
Molecular Weight 374.433
Flash Point 331.7±31.5 °C
Exact Mass 374.216522
LogP 0.66
Vapour Pressure 0.0±3.9 mmHg at 25°C
Index of Refraction 1.504
Storage condition 2-8°C