2-Methyl-2-propanyl 1-pyrrolidinecarboxylate
Names
[ CAS No. ]:
86953-79-9
[ Name ]:
2-Methyl-2-propanyl 1-pyrrolidinecarboxylate
[Synonym ]:
tert-butyl pyrrolidine-1-carboxylate
MFCD00216581
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
221.4±9.0 °C at 760 mmHg
[ Molecular Formula ]:
C9H17NO2
[ Molecular Weight ]:
171.237
[ Flash Point ]:
87.7±18.7 °C
[ Exact Mass ]:
171.125931
[ PSA ]:
29.54000
[ LogP ]:
1.49
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.473
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NA 1993 / PGIII
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Org. Chem. 76(15) , 5936-53, (2011)
A comprehensive study of the enantioselective Pd-catalyzed α-arylation of N-Boc pyrrolidine has been carried out. The protocol involves deprotonation of N-Boc pyrrolidine using s-BuLi/(-)-sparteine in...
Asymmetric synthesis of enantioenriched (+)-elaeokanine A.J. Org. Chem. 71(15) , 5674-8, (2006)
The key transformation in the total synthesis of (+)-elaeokanine A was accomplished by asymmetric deprotonation of N-Boc pyrrolidine, followed by the reaction of the in situ generated enantioenriched ...
Enantioselective, palladium-catalyzed α-arylation of N-boc-pyrrolidine. Campos KR, et al.J. Am. Chem. Soc. 128(11) , 3538-3539, (2006)