PRX-08066 Maleic acid

Names

[ Name ]:
PRX-08066 Maleic acid

[Synonym ]:
Benzonitrile, 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl]methyl]-2-fluoro-, (2Z)-2-butenedioate (1:1)
5-({4-[(6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl}methyl)-2-fluorobenzonitrile (2Z)-2-butenedioate (1:1)

Biological Activity

[Description]:

PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that causes selective vasodilation of pulmonary arteries.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT2B Receptor:3.4 nM (IC50)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₁ClFN₅O₄S

[ Molecular Weight ]:
517.96

[ Exact Mass ]:
517.098694

[ PSA ]:
167.68000

[ LogP ]:
4.15468

[ Storage condition ]:
-20℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.