Licochalcone E

Names

[ Name ]:
Licochalcone E

Biological Activity

[Description]:

Licochalcone E, a flavonoid compound isolated from Glycyrrhiza inflate, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> Akt

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK

Research Areas >> Inflammation/Immunology

[Target]

AKT, MAPK, NF-κB[1].

[References]

[1]. Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂O₄

[ Molecular Weight ]:
338.4

Related Compounds

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