Fmoc-3VVD-OH

Names

[ CAS No. ]:
863971-44-2

[ Name ]:
Fmoc-3VVD-OH

[Synonym ]:
FMOC-3AA-OH
Fmoc-Meval-val-dolaisoleucine-OH

Biological Activity

[Description]:

Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Michinori Akaiwa, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018 May 31;3(5):5212-5221.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₆H₅₁N₃O₇

[ Molecular Weight ]:
637.80604

Related Compounds

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