863971-44-2

863971-44-2 structure

Name: Fmoc-3VVD-OH
Chemical Name: (5S,9S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,9-diisopropyl-12-Methoxy-4,10-diMethyl-3,6,8-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
CAS Number: 863971-44-2
Molecular Formula: C₃₆H₅₁N₃O₇
Molecular Weight: 637.80604
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-29 23:03:11
Modify Date: 2024-01-11 19:11:03
Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	(5S,9S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,9-diisopropyl-12-Methoxy-4,10-diMethyl-3,6,8-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
Synonyms	FMOC-3AA-OH Fmoc-Meval-val-dolaisoleucine-OH

Description	Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Michinori Akaiwa, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018 May 31;3(5):5212-5221.

Molecular Formula	C₃₆H₅₁N₃O₇
Molecular Weight	637.80604