N,N-Dimethyl-1-naphthylamine

Names

[ CAS No. ]:
86-56-6

[ Name ]:
N,N-Dimethyl-1-naphthylamine

[Synonym ]:
EINECS 201-682-4
N,N-dimethylnaphthalen-1-amine
MFCD00003919

Biological Activity

[Description]:

N,N-Dimethyl-1-naphthylamine is an aromatic amine and a dye. N,N-Dimethyl-1-naphthylamine can be used in nitrate reduction test[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kasali A. Bello, et al. Violet to cyan azo dyes derived from 4-amino-3-nitrobenzaldehyde as diazo component. Dyes and Pigments. 1989, 65-76.

[2]. Tsikas D. Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine/nitric oxide area of research. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 15;851(1-2):51-70.

Chemical & Physical Properties

[ Density]:
1.042 g/mL at 25 °C(lit.)

[ Boiling Point ]:
139-140 °C13 mm Hg(lit.)

[ Molecular Formula ]:
C₁₂H₁₃N

[ Molecular Weight ]:
171.23800

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
171.10500

[ PSA ]:
3.24000

[ LogP ]:
2.90580

[ Index of Refraction ]:
n20/D 1.622(lit.)

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QM2825000

CHEMICAL NAME :: 1-Naphthylamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 86-56-6

BEILSTEIN REFERENCE NO. :: 1424075

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H13-N

MOLECULAR WEIGHT :: 171.26

WISWESSER LINE NOTATION :: L66J BN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,265,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1111 No. of Facilities: 43 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 383 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1111 No. of Facilities: 150 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2006 (estimated) No. of Female Employees: 1662 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R22;R36/37/38;R51/53

[ Safety Phrases ]:
S26-S36-S61-S37/39-S29

[ RIDADR ]:
UN 1369/2810

[ WGK Germany ]:
2

[ RTECS ]:
QM2825000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
2921450090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921450090

[ Summary ]:
2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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