2,3-Dimethoxybenzaldehyde

Names

[ CAS No. ]:
86-51-1

[ Name ]:
2,3-Dimethoxybenzaldehyde

[Synonym ]:
4-Diethoxybenzene
Orthoveratraldehyde
MFCD00003309
3-DiMethoxybenzaldehyde
2-VERATRALDEHYDE
2,3-Dimethoxybenzaldehyde
2,3-Dimethoxybenzald
EINECS 201-677-7
Benzaldehyde, 2,3-dimethoxy-
dimethoxybenzaldehyde
2,3-dimethoxyphenylaldehyde
2,3-dimethoxtbenzaldehyde
O-VERATRIC ALDEHYDE
O-VERATRALDEHYDE
2,3-dimethoxy-benzaldehyde
2,3-dimethyoxybenzaldehyde
2,3-dimethoxylbenzaldehyde

Biological Activity

[Description]:

2,3-Dimethoxybenzaldehyde (o-Veratraldehyde) is a benzaldehyde analog, with high antifungal activity (MIC=2.5 mM) 2,3-Dimethoxybenzaldehyde (o-Veratraldehyde) could be used for the synthesis of berberine[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Infection

[References]

[1]. Kim JH, et al. Antifungal activity of redox-active benzaldehydes that target cellular antioxidation. Ann Clin Microbiol Antimicrob.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
266.7±20.0 °C at 760 mmHg

[ Melting Point ]:
48-52 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀O₃

[ Molecular Weight ]:
166.174

[ Flash Point ]:
105.8±8.2 °C

[ Exact Mass ]:
166.062988

[ PSA ]:
35.53000

[ LogP ]:
1.63

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.534

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CU5732000

[ HS Code ]:
29124900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Antifungal activity of redox-active benzaldehydes that target cellular antioxidation.

Ann. Clin. Microbiol. Antimicrob. 10 , 23, (2011)

Disruption of cellular antioxidation systems should be an effective method for control of fungal pathogens. Such disruption can be achieved with redox-active compounds. Natural phenolic compounds can ...

Engineering Klebsiella sp. 601 multicopper oxidase enhances the catalytic efficiency towards phenolic substrates.

BMC Biochem. 12 , 30, (2011)

Structural comparison between bacterial CueO and fungal laccases has suggested that a charged residue Glu (E106) in CueO replaces the corresponding residue Phe in fungal laccases at the gate of the tu...