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5'-O-TBDMS-N2-ibu-dG

Names

[ CAS No. ]:
85326-10-9

[ Name ]:
5'-O-TBDMS-N2-ibu-dG

[Synonym ]:
N2-isobutyryl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine
N2-isobutyryl-5'-O-(tert-butyldimethylsilyl) -2'-deoxyguanosine
5'-O-tert-butyldimethylsilyl-N2-isobutyryl-2'-deoxyguanosine
N-{9-[(2R,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-isobutyramide
5'-O-(tert-butyldimethylsilyl)-2-N-isobutyryl-deoxyguanosine
5'-O-tert-butyldimethylsilyl-N2-isobutyryl-2'-deoxy-3'-beta-guanosine
N2-isobutyryl-5'-O-tert-butyldimethylsilyl-2'-deoxyguanosine

Biological Activity

[Description]:

5'-O-TBDMS-N2-ibu-dG is a nucleoside derivative and can be used for lead compounds synthesis with anti-bovine viral diarrhea virus activity[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Kohji Seio, et al. Synthesis of benzodithiol-2-yl-substituted nucleoside derivatives as lead compounds having anti-bovine viral diarrhea virus activity. J Med Chem. 2004 Oct 7;47(21):5265-75.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H33N5O5Si

[ Molecular Weight ]:
451.59200

[ Exact Mass ]:
451.22500

[ PSA ]:
131.36000

[ LogP ]:
2.45730

Related Compounds