Guaiapate

Names

[ CAS No. ]:
852-42-6

[ Name ]:
Guaiapate

[Synonym ]:
8-<2-Methoxy-phenoxy>-1-piperidino-3.6-dioxa-octan
EINECS 212-713-6
Guaiapato [DCIT]
Guayapato [INN-Spanish]
Guaiapate
1-[8-(2-methoxy-phenoxy)-3,6-dioxa-octyl]-piperidine
1-(2-Methoxyphenoxy)-3,6-dioxa-8-(N-piperidino)-octane
Guaiapatum [INN-Latin]
Mg 5454
Klamar

Biological Activity

[Description]:

Guaiapate is an antitussive drug.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[References]

[1]. Ferro AM, et al. Clinical evaluation of a synthetic cough sedative: guaiapate. Clin Ter. 1978 Aug 31;86(4):355-67.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.056 g/cm3

[ Boiling Point ]:
426ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₂₉NO₄

[ Molecular Weight ]:
323.42700

[ Flash Point ]:
119.3ºC

[ Exact Mass ]:
323.21000

[ PSA ]:
40.16000

[ LogP ]:
2.53100

[ Index of Refraction ]:
1.505

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN1062500

CHEMICAL NAME :: Piperidine, 1-(2-(2-(2-(o-methoxyphenoxy)ethoxy)ethoxy)ethyl)-

CAS REGISTRY NUMBER :: 852-42-6

BEILSTEIN REFERENCE NO. :: 1323331

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H29-N-O4

MOLECULAR WEIGHT :: 323.48

WISWESSER LINE NOTATION :: T6NTJ A2O2O2OR BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 82 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - local anesthetic Behavioral - general anesthetic Behavioral - analgesia

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,542,1965

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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