8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

Names

[ Name ]:
8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

Biological Activity

[Description]:

RSV L-protein-IN-4 (Compound C) is a noncompetitive RSV polymerase inhibitor (IC50: 0.88 μM). RSV L-protein-IN-4 shows antiviral activity against RSV strains (EC50: 0.25 μM)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> RSV

[Target]

0.88 μM (RSV polymerase)[1]

[References]

[1]. Liuzzi M, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005 Oct;79(20):13105-15.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₅N₅O₆

[ Molecular Weight ]:
585.65

8-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione1H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione

Names

Biological Activity

Chemical & Physical Properties

Related Compounds