YM-53403

Names

[ Name ]:
YM-53403

[Synonym ]:
6-{4-[(2-Biphenylylcarbonyl)amino]benzoyl}-N-cyclopropyl-5,6-dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxamide
4H-Thieno[3,2-d][1]benzazepine-2-carboxamide, 6-[4-[([1,1'-biphenyl]-2-ylcarbonyl)amino]benzoyl]-N-cyclopropyl-5,6-dihydro-

Biological Activity

[Description]:

YM-53403 (YM53403) is a specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays; displays 100-fold more potent than ribavirin, an attractive compound for the treatment of RSV infection.

[References]

References 1. Sudo K, et al. Antiviral Res. 2005 Feb;65(2):125-31. 2. Tiong-Yip CL, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3867-73. View Related Products by Target RSV

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
787.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₂₉N₃O₃S

[ Molecular Weight ]:
583.699

[ Flash Point ]:
430.3±32.9 °C

[ Exact Mass ]:
583.192932

[ LogP ]:
5.83

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.734

Related Compounds

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