Bevasiranib sodium

Names

[ CAS No. ]:
849758-52-7

[ Name ]:
Bevasiranib sodium

Biological Activity

[Description]:

Bevasiranib sodium is a siRNA designed to silence the genes that produce vascular endothelial growth factor (VEGF). It is widely accepted that vascular endothelial growth factor (VEGF) is a key component in the pathogenesis of choroidal neo-vascularization (CNV), which is a precursor to wet age-related macular degeneration (wet AMD).

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR

[References]

[1]. Garba AO, Mousa SA. Bevasiranib for the treatment of wet, age-related macular degeneration. Ophthalmol Eye Dis. 2010;2:75-83.  

[2]. Dejneka NS, Wan S, Bond OS, Kornbrust DJ, Reich SJ. Ocular biodistribution of bevasiranib following a single intravitreal injection to rabbit eyes. Mol Vis. 2008;14:997-1005.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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