G3-C12
Names
[ CAS No. ]:
848301-94-0
[ Name ]:
G3-C12
Biological Activity
[Description]:
G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity.
[Related Catalog]:
[Target]
Kd: 88 nM (Galectin-3)[1]
[In Vitro]
G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].
[References]
[Related Small Molecules]
Captisol
|
Cyclosporin A
|
H2DCFDA
|
0MPTP hydrochloride
|
GW4869
|
Etomoxir
|
TD139
|
Mitoquinone mesylate
|
GSK2795039
|
JC-1
|
BAPTA-AM
|
AP 20187
|
Setanaxib (GKT137831)
|
D-Luciferin
|
Crotaline
Chemical & Physical Properties
[ Molecular Formula ]:
C74H115N23O23S2
[ Molecular Weight ]:
1758.98
[ Storage condition ]:
2-8℃