4-Methylhistamine hydrochloride

Names

[ Name ]:
4-Methylhistamine hydrochloride

Biological Activity

[Description]:

4-Methylhistamine (hydrochloride) is a potent, high affinity H4 receptor agonist Ki of 7 nM. 4-Methylhistamine (hydrochloride) displays more than 100-fold selectivity over other human histamine receptor subtypes[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[References]

[1]. Lim HD, et.al. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J Pharmacol Exp Ther. 2005 Sep;314(3):1310-21.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₂ClN₃

[ Molecular Weight ]:
161.63

Related Compounds

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