Phanquinone

Names

[ CAS No. ]:
84-12-8

[ Name ]:
Phanquinone

[Synonym ]:
Fanquinona
5,6-Dioxo-5,6-dihydro-4,7-phenanthroline
[4,7]Phenanthroline-5,6-dione
phanquinonum [INN_en]
[4,7]Phenanthrolin-5,6-dion
4,7-Phenanthroline-5,6-dione
Phanquinone
Entobex
Phanchinone
Entronon
4,7-Phenanthrolene-5,6-quinone
Phanquinonum
Phanchinonum
phanquone
Enthohex

Biological Activity

[Description]:

Phanquone (11925 C; Entronon) derives from a hydride of a 4,7-phenanthroline. Phanquone is applied as an original precolumn derivatization reagent for amino acids[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Gotti R, et al. Phanquinone as a suitable derivatization reagent in micellar electrokinetic chromatography and HPLC analysis of amino acids. J Sep Sci. 2006;29(9):1259-1267.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
456.1±20.0 °C at 760 mmHg

[ Melting Point ]:
295° (dec)

[ Molecular Formula ]:
C₁₂H₆N₂O₂

[ Molecular Weight ]:
210.19

[ Flash Point ]:
229.1±28.2 °C

[ Exact Mass ]:
210.042923

[ PSA ]:
59.92000

[ LogP ]:
0.15

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.678

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SF8423000

CHEMICAL NAME :: 4,7-Phenanthroline-5,6-dione

CAS REGISTRY NUMBER :: 84-12-8

BEILSTEIN REFERENCE NO. :: 0160657

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H6-N2-O2

MOLECULAR WEIGHT :: 210.20

WISWESSER LINE NOTATION :: T B666 FN HVV KNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 6300 mg/kg/21D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Mold - Aspergillus nidulans

DOSE/DURATION :: 1 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 26,159,1974

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%