Cathepsin D and E FRET Substrate

Names

[ Name ]:
Cathepsin D and E FRET Substrate

[Synonym ]:
N-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N-(2,4-dinitrophenyl)-L-lysyl-D-argininamide
D-Argininamide, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucyl-N-(2,4-dinitrophenyl)-L-lysyl-

Biological Activity

[Description]:

Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[References]

[1]. Y Yasuda, et al. Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D. J Biochem

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₈₅H₁₂₂N₂₂O₁₉

[ Molecular Weight ]:
1756.014

[ Exact Mass ]:
1754.925659

[ LogP ]:
6.09

[ Index of Refraction ]:
1.651

Related Compounds

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