CAY10591

Names

[ Name ]:
CAY10591

[Synonym ]:
2-Amino-N-cyclopentyl-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
SIRT1 Activator 3
1H-Pyrrolo[2,3-b]quinoxaline-3-carboxamide, 2-amino-N-cyclopentyl-1-(3-methoxypropyl)-

Biological Activity

[Description]:

SIRT1 activator 3 is a potent activator of Sirt1 and suppresses TNF-α in a dose-dependent manner. SIRT1 activator 3 has the potential for anti-obesity or anti-diabetic researches[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin

Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

Research Areas >> Metabolic Disease

[References]

[1]. Nayagam VM, et al. SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents. J Biomol Screen. 2006 Dec;11(8):959-67.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
651.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₅N₅O₂

[ Molecular Weight ]:
367.445

[ Flash Point ]:
347.7±31.5 °C

[ Exact Mass ]:
367.200836

[ PSA ]:
95.06000

[ LogP ]:
2.84

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.693

Related Compounds

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