Cetirizine methyl ester

Names

[ CAS No. ]:
83881-46-3

[ Name ]:
Cetirizine methyl ester

[Synonym ]:
methyl [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate
(2-{4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetic acid methyl ester
methyl-2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate
Cetirizine Methyl Ester
Cetirizine Methanol Adduct

Biological Activity

[Description]:

Cetirizine methyl ester is an impurity of Cetirizine (HY-17042). Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor
Research Areas >> Endocrinology
Research Areas >> Inflammation/Immunology
Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C22H27ClN2O3

[ Molecular Weight ]:
402.91400

[ Exact Mass ]:
402.17100

[ PSA ]:
42.01000

[ LogP ]:
3.11240

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds