4-Amino-2-methyl-1-naphthol
Names
[ CAS No. ]:
83-70-5
[ Name ]:
4-Amino-2-methyl-1-naphthol
[Synonym ]:
4-Amino-2-methyl-1-naphthol
4-Amino-2-methyl-1-naphthol hci
synkaminbase
4-amino-2-methylnaphthalen-1-ol
4-amino-2-methyl-1-naphthaleno
kayvisyn
4-Amino-1-hydroxy-2-methyl-naphthalin
1-Naphthalenol, 4-amino-2-methyl-
2-methyl-4-amino-1-naphthol
synkamin
4-amino-2-methyl-1-naphtho
4-amino-2-methyl-1-naphthalenol
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 28 μM (PKM2), 191 μM PKM1, 120 μM (PKL)[2]
[In Vitro]
[References]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
385.1±30.0 °C at 760 mmHg
[ Molecular Formula ]:
C11H11NO
[ Molecular Weight ]:
173.211
[ Flash Point ]:
186.7±24.6 °C
[ Exact Mass ]:
173.084061
[ PSA ]:
46.25000
[ LogP ]:
1.40
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.712
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL3350000
- CHEMICAL NAME :
- 1-Naphthol, 4-amino-2-methyl-
- CAS REGISTRY NUMBER :
- 83-70-5
- BEILSTEIN REFERENCE NO. :
- 2719282
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C11-H11-N-O
- MOLECULAR WEIGHT :
- 173.23
- WISWESSER LINE NOTATION :
- L66J BQ C1 EZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 17,1339,1967
Safety Information
[ HS Code ]:
2922299090
Synthetic Route
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%