Naphth(1,8-cd)-1,2-oxathiole, 2,2-dioxide

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
419.5±18.0 °C at 760 mmHg

[ Melting Point ]:
154-157 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₀H₆O₃S

[ Molecular Weight ]:
206.218

[ Flash Point ]:
207.5±21.2 °C

[ Exact Mass ]:
206.003769

[ PSA ]:
51.75000

[ LogP ]:
2.40

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.729

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[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R38

[ Safety Phrases ]:
S22-S28

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934991000

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2934991000

[ Summary ]:
2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 1. Synthesis and studies on the reactivity toward model nucleophiles of the (13)C-labeled skin sensitizers hex-1-ene- and hexane-1,3-sultones.

Chem. Res. Toxicol. 14(1) , 110-7, (2001)

The potent skin sensitizers hex-1-ene- and hexane-1,3-sultone have been synthesized isotopically labeled with (13)C at reactive sites. The reactivity of 2-[(13)C]- and 3-[(13)C]hex-1-ene-1,3-sultones ...

Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 2. nmr studies of the covalent binding of the (13)c-labeled skin sensitizers 2-[13C]- and 3-[13C]hex-1-ene- and 3-[13C]hexane-1,3-sultones to human serum albumin.

Chem. Res. Toxicol. 14(1) , 118-26, (2001)

3-[(13)C]- and 2-[(13)C]hex-1-ene-1,3-sultones (1a and 1b, respectively) and 3-[(13)C]hex-1-ene-1,3-sultone 2a were incubated with human serum albumin in phosphate buffer at pH 8.1. In both cases, the...

4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.

J. Med. Chem. 52(6) , 1582-91, (2009)

We report the synthesis and antiviral activity of a new family of non-nucleoside antivirals, derived from the 4-keto-1,2-oxathiole-2,2-dioxide (beta-keto-gamma-sultone) heterocyclic system. Several 4-...

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