Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-

Names

[ Name ]:
Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-

[Synonym ]:
Acetamide, N-[9-[(6aR,8R,9R,9aS)-tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-6H-furo[3,2-f]-1,3,5,2,4-trioxadisilocin-8-yl]-9H-purin-6-yl]-
N-{9-[(6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-9H-purin-6-yl}acetamide

Biological Activity

[Description]:

3',5'-TIPS-N-Ac-Adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₂₄H₄₁N₅O₆Si₂

[ Molecular Weight ]:
551.78

[ Exact Mass ]:
551.259521

[ Index of Refraction ]:
1.588

[ Storage condition ]:
2-8℃

Related Compounds

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