UNII:1134E5H2KV

Names

[ CAS No. ]:
822-87-7

[ Name ]:
UNII:1134E5H2KV

[Synonym ]:
Cyclohexanone, 2-chloro-
EINECS 212-505-5
UNII:1134E5H2KV
MFCD00001626
2-chlorocyclohexan-1-one
2-Chlorocyclohexanone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
203.3±0.0 °C at 760 mmHg

[ Melting Point ]:
23 °C(lit.)

[ Molecular Formula ]:
C₆H₉ClO

[ Molecular Weight ]:
132.588

[ Flash Point ]:
82.2±0.0 °C

[ Exact Mass ]:
132.034195

[ PSA ]:
17.07000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.465

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GW1225000

CHEMICAL NAME :: Cyclohexanone, 2-chloro-

CAS REGISTRY NUMBER :: 822-87-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H9-Cl-O

MOLECULAR WEIGHT :: 132.60

WISWESSER LINE NOTATION :: L6VTJ BG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 830 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - coma Behavioral - analgesia

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 370 nmol/plate

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 45,305,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37-S37/39

[ RIDADR ]:
UN 3335 9

[ WGK Germany ]:
3

[ RTECS ]:
GW1225000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

alpha-chloroepoxides. 2. Mutagenicity of 1-chlorocyclohexene oxide and its thermal isomerization product, 2-chlorocyclohexanone.

Chem. Biol. Interact. 45(3) , 305-14, (1983)

The pseudo-first-order hydrolysis rate constants in pH 7.4 buffer-acetone solution are reported for 1-chlorocyclohexene oxide and 2-chlorocyclohexanone at 0, 25 and 37 degrees C. The rate constants, i...