Clomazone

Names

[ Name ]:
Clomazone

[Synonym ]:
2-[(2-chlorophenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one
gamit
Dimethazon
COMMAND,100MG,NEAT
Clomazone
MFCD00072457
2-(2-Chlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one
Dimethazone
fenoxan
Command
2-(2-Chlorobenzyl)-4,4-dimethyl-3-isoxazolidinone
2-[(2-Chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone
Clomazon
2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one
Isooxadiazon
3-Isoxazolidinone, 2-[(2-chlorophenyl)methyl]-4,4-dimethyl-
Comazone

Biological Activity

[Description]:

Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ewa Szpyrka , et al. Influence of a Commercial Biological Fungicide ContainingTrichoderma harzianum Rifai T-22 on Dissipation Kinetics and Degradation of Five Herbicides in Two Types of Soil. Molecules. 2020 Mar 18;25(6):1391.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
317.6±44.0 °C at 760 mmHg

[ Melting Point ]:
25°C

[ Molecular Formula ]:
C₁₂H₁₄ClNO₂

[ Molecular Weight ]:
239.698

[ Flash Point ]:
145.9±28.4 °C

[ Exact Mass ]:
239.071304

[ PSA ]:
29.54000

[ LogP ]:
2.17

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.551

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NY2977000

CHEMICAL NAME :: 3-Isoxazolidinone, 2-((2-chlorophenyl)methyl)-4,4-dimethyl-

CAS REGISTRY NUMBER :: 81777-89-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H14-Cl-N-O2

MOLECULAR WEIGHT :: 239.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1369 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,178,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4800 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,178,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,178,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,178,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,178,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H332-H315-H319

[ Precautionary Statements ]:
P261-P301 + P312 + P330-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2902

[ RTECS ]:
NY2977000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2934999027

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999027

[ Summary ]:
2934999027 3-isopropyl-1h-benzo[c][1,2,6]thiadiazin-4(3h)-one 2,2-dioxide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Articles

Natural impacted freshwaters: in situ use of alginate immobilized algae to the assessment of algal response.

Ecotoxicology 18(4) , 464-9, (2009)

The objective of this study was to investigate the feasibility of an in situ phytotoxicity test using alginate-immobilized algae for 60 days, in the assessment of water quality in an impacted small pe...

Mitigation of dimethazone residues in soil and runoff water from agricultural field.

J. Environ. Sci. Health B 46(1) , 76-83, (2011)

Dimethazone, also known as clomazone [2-[(2-chlorophenyl) methyl]- 4,4-dimethyl-3-isoxaolidinone] is a pre-emergent nonionic herbicide commonly used in agriculture. A field study was conducted on a si...

Herbicide clomazone effects on δ-aminolevulinic acid activity and metabolic parameters in Cyprinus carpio.

Bull. Environ. Contam. Toxicol. 92(4) , 393-8, (2014)

The objective of this study was to investigate δ-aminolevulinic acid (δ-ALA-D) activity and metabolic parameters of Cyprinus carpio exposed to clomazone herbicide. Fish were exposed 2.5, 5, 10 and 20 ...

Related Compounds

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