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cafestol acetate

Names

[ CAS No. ]:
81760-48-7

[ Name ]:
cafestol acetate

[Synonym ]:
MFCD00133152
O-Acetyl-cafestol

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
474.6ºC at 760mmHg

[ Molecular Formula ]:
C22H30O4

[ Molecular Weight ]:
358.47100

[ Flash Point ]:
240.8ºC

[ Exact Mass ]:
358.21400

[ PSA ]:
59.67000

[ LogP ]:
4.21010

[ Index of Refraction ]:
1.578

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

DownStream

Articles

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.

Food Chem. Toxicol. 46 , 1230-1238, (2008)

Coffee drinking appears to reduce cancer risk in liver and colon. Such chemoprevention may be caused by the diterpenes kahweol and cafestol (K/C) contained in unfiltered beverage. In animals, K/C trea...

Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.

Toxicol. Lett. 173 , 80-87, (2007)

There is an increasing evidence that oxidative stress is implicated in the processes of inflammation and carcinogenesis. It has been shown that kahweol and cafestol, coffee-specific diterpenes, exhibi...

Inhibition of the fungal fatty acid synthase type I multienzyme complex.

Proc. Natl. Acad. Sci. U. S. A. 105 , 12803-8, (2008)

Fatty acids are among the major building blocks of living cells, making lipid biosynthesis a potent target for compounds with antibiotic or antineoplastic properties. We present the crystal structure ...


More Articles


Related Compounds

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