1-Bromo-2-butanone
Names
[ CAS No. ]:
816-40-0
[ Name ]:
1-Bromo-2-butanone
[Synonym ]:
1-Bromo-2-butanone
2-Butanone, 1-bromo-
MFCD00000207
1-bromobutan-2-one
EINECS 212-431-3
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
155.9±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C4H7BrO
[ Molecular Weight ]:
151.002
[ Flash Point ]:
68.3±0.0 °C
[ Exact Mass ]:
149.968018
[ PSA ]:
17.07000
[ LogP ]:
1.07
[ Vapour Pressure ]:
3.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.453
[ Storage condition ]:
Keep Cold
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EL7000000
- CHEMICAL NAME :
- 2-Butanone, 1-bromo-
- CAS REGISTRY NUMBER :
- 816-40-0
- BEILSTEIN REFERENCE NO. :
- 0741894
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C4-H7-Br-O
- MOLECULAR WEIGHT :
- 151.02
- WISWESSER LINE NOTATION :
- E1V2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/m3/10M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: No.9-4-1-9,1943
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn,Xi,F
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S27-S36/37/39
[ RIDADR ]:
1693
[ WGK Germany ]:
3
[ RTECS ]:
EL7000000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
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The residue C221 on pyruvate decarboxylase (EC. 4.1.1.1) from Saccharomyces cerevisiae has been shown to be the site where the substrate activation cascade is triggered [Baburina et al. (1994) Biochem...
Tetrahedron Lett. 47 , 3889, (2006)