5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

Names

[ Name ]:
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

[Synonym ]:
5'-dimethoxytrityl 2'-tert-butyldimethyl silyl N-isobutyrylguanosine
(2)N-isobutyryl-5'O-dimetoxytrityl-3'O-tert-butyldimethylsilyl guanosine
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine
N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl guanosine
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
2-N-isobutyryl-2'-O-tert-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)guanosine
5'-O-dimethoxytrityl-2'-O-tert-butyldimethylsilyl-N2-isobutyryl guanosine

Biological Activity

[Description]:

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Thomas P Blaisdell, et al. Practical silyl protection of ribonucleosides. Org Lett. 2013 Sep 20;15(18):4710-3.

Chemical & Physical Properties

[ Density]:
1.25

[ Molecular Formula ]:
C₄₁H₅₁N₅O₈Si

[ Molecular Weight ]:
769.95800

[ Exact Mass ]:
769.35100

[ PSA ]:
159.31000

[ LogP ]:
6.87400

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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