COUMACHLOR
Names
[ CAS No. ]:
81-82-3
[ Name ]:
COUMACHLOR
[Synonym ]:
UNII:UCD8XZW42P
3-(1-(4-Chlorophenyl)-3-oxobutyl)-4-hydroxy-2H-1-benzopyran-2-one (9CI)
MFCD00012094
2H-1-Benzopyran-2-one, 3-[1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-
3-(a-Acetonyl-p-chlorobenzyl)-4-hydroxycoumarin
tomorin
3-[(1RS)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxycoumarin
3-(a-p-Chlorophenyl-b-acetylethyl)-4-hydroxycoumarin
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
Coumachlor
Geigy Rodenticide Exp.332
FAMARIN
rac-3-[(1R)-1-(4-chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-1-benzopyran-2-one
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-2H-chromen-2-one
ratilan
P-CHLOROWARFARIN
cumachloor
kumachlor
(±)-3-(1-(p-Chlorophenyl)-3-oxobutyl)-4-hydroxycoumarin
EINECS 201-378-1
(±)-Coumachlor
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
543.1±50.0 °C at 760 mmHg
[ Melting Point ]:
168-170 °C(lit.)
[ Molecular Formula ]:
C19H15ClO4
[ Molecular Weight ]:
342.773
[ Flash Point ]:
282.3±30.1 °C
[ Exact Mass ]:
342.065887
[ PSA ]:
67.51000
[ LogP ]:
4.01
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.641
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GN4830000
- CHEMICAL NAME :
- Coumarin, 3-(alpha-acetonyl-p-chlorobenzyl)-4-hydroxy-
- CAS REGISTRY NUMBER :
- 81-82-3
- BEILSTEIN REFERENCE NO. :
- 1689759
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H15-Cl-O4
- MOLECULAR WEIGHT :
- 342.79
- WISWESSER LINE NOTATION :
- T66 BOVJ DY1V1&R DG& EQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 187 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,186,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 392 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 221 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 30,531,1995
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H373-H412
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R48/22;R52/53
[ Safety Phrases ]:
S37-S61
[ RIDADR ]:
UN 2811 6.1/PG 1
[ WGK Germany ]:
2
[ RTECS ]:
GN4830000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Electrophoresis 35(19) , 2807-18, (2014)
A generic chiral separation strategy for the analysis of acidic compounds in CEC is proposed in completion of an earlier defined strategy for nonacidic compounds. The screening step of this strategy u...
Single-step approach for fabrication of vancomycin-bonded silica monolith as chiral stationary phase.J. Chromatogr. A. 1358 , 208-16, (2014)
A vancomycin-bonded silica monolithic column for capillary electrochromatography (CEC) was prepared by a single-step in situ sol-gel approach. This sol-gel process incorporates a synthetic sol-gel pre...
Toxicology and histopathology of some rodenticides and palatable food items combinations on the common mice Mus musculus var. albus in Egypt.Commun. Agric. Appl. Biol. Sci. 68(4 Pt B) , 771-87, (2003)
In this study the palatability tests of certain food items as attractants in the poisoned-baits for the albino mouse Mus musculus var. albus showed that the food items of treacle, maize oil, dry or we...