Lysine-methotrexate

Names

[ CAS No. ]:
80407-56-3

[ Name ]:
Lysine-methotrexate

[Synonym ]:
(S)-6-Amino-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-hexanoic acid

Biological Activity

[Description]:

Lysine-methotrexate, an analogue of Methotrexate (HY-14519), is a dihydrofolate reductase (DHFR) inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate

Research Areas >> Inflammation/Immunology

[References]

[1]. Kempton RJ, et al. Lysine and ornithine analogues of methotrexate as inhibitors of dihydrofolate reductase. J Med Chem. 1982 Apr;25(4):475-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₇N₉O₃

[ Molecular Weight ]:
453.49800

[ Exact Mass ]:
453.22400

[ PSA ]:
199.26000

[ LogP ]:
2.78620

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.