Paraffin oil

Names

[ Name ]:
Paraffin oil

[Synonym ]:
EINECS 232-384-2

Biological Activity

[Description]:

Light Liquid Paraffin can be used as an excipient, such as excipient, lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
0.85 g/mL at 20 °C

[ Boiling Point ]:
300 °C

[ Melting Point ]:
-24 °C

[ Molecular Formula ]:
C₁₅H₁₁ClO₇

[ Molecular Weight ]:
338.69664

[ Flash Point ]:
>300°C

[ Appearance of Characters ]:
light oil | white

[ Index of Refraction ]:
n20/D 1.467(lit.)

[ Storage condition ]:
Store at room temperature.

[ Water Solubility ]:
Soluble in ether. Sparingly soluble in ethanol. Not miscible or difficult to mix in water.

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H304

[ Precautionary Statements ]:
P301 + P310-P331

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
PY8047000

Articles

Fourier transform infrared spectroscopy imaging of live epithelial cancer cells under non-aqueous media.

J. Clin. Pathol. 66(4) , 312-8, (2013)

Fourier transform infrared (FT-IR) imaging is increasingly being applied to biomedical specimens, but strong IR absorption by water complicates live cell imaging. This study investigates the viability...

Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.

Biol. Reprod. 80 , 286-94, (2008)

A universal response to cellular stress is the expression of transformation-related protein 53 (TRP53). This transcription factor reduces cell proliferation and/or survival and is classed as a tumour ...

Paraffin oil as a "methane vector" for rapid and high cell density cultivation of Methylosinus trichosporium OB3b.

Appl. Microbiol. Biotechnol. 83(4) , 669-77, (2009)

Slow growth and relatively low cell densities of methanotrophs have limited their uses in industrial applications. In this study, a novel method for rapid cultivation of Methylosinus trichosporium OB3...

Related Compounds

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