23-O-DesMycinosyl-tylosin

Names

[ Name ]:
23-O-DesMycinosyl-tylosin

[Synonym ]:
O-demycinosyltylosin
demycinosyltylosin
1-(4-hydroxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
1-(4-hydroxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide
23-demycinosyltylosin

Biological Activity

[Description]:

23-O-Demycinosyltylosin (23-DMT; 23-Demycinosyltylosin) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

23-O-Demycinosyltylosin 抑制对大环内酯敏感的革兰氏阳性细菌生长[1]。

[References]

[1]. Cacciapuoti AF, et al. Microbiological and pharmacokinetic studies of acyl demycinosyltylosin and related tylosin derivatives. J Antibiot (Tokyo). 1990 Sep;43(9):1131-6.

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
890.7ºC at 760 mmHg

[ Molecular Formula ]:
C₃₈H₆₃NO₁₃

[ Molecular Weight ]:
741.90600

[ Flash Point ]:
492.5ºC

[ Exact Mass ]:
741.43000

[ PSA ]:
201.75000

[ LogP ]:
1.67350

[ Index of Refraction ]:
1.553

Synthetic Route

Click to get detail synthetic route

Related Compounds

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