Pipecolic acid-d9

Names

[ Name ]:
Pipecolic acid-d9

[Synonym ]:
Dihydrobaikiane-d9
Hexahydro-2-picolinic acid
Pipecolinic Acid-d9
Piperolinic Acid-d9
2-Pipecolinic Acid-d9
Pipecolic Acid-d9
|A-Pipecolinic Acid-d9
DL-Pipecolic Acid-d9
2-Carboxypiperidine-d9

Biological Activity

[Description]:

Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid, a metabolite of Lysine, is an important precursor of many useful microbial secondary metabolites. Pipecolic acid can be used as a diagnostic marker of Pyridoxine-dependent epilepsy[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. He M, et al. Pipecolic acid in microbes: biosynthetic routes and enzymes. J Ind Microbiol Biotechnol. 2006 Jun;33(6):401-7.

[3]. Plecko B, et, al. Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy. Neuropediatrics. 2005 Jun;36(3):200-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₂D₉NO₂

[ Molecular Weight ]:
138.21

[ Exact Mass ]:
138.13500

[ PSA ]:
49.33000

[ LogP ]:
0.54190

Related Compounds

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