Ceftazidime Pentahydrate

Names

[ Name ]:
Ceftazidime Pentahydrate

[Synonym ]:
MFCD00153936
EINECS 276-715-9
Pyridinium, 1-[[(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Ceftazidime

Biological Activity

[Description]:

Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61.

Chemical & Physical Properties

[ Melting Point ]:
>150ºC(dec.)

[ Molecular Formula ]:
C₂₂H₃₂N₆O₁₂S₂

[ Molecular Weight ]:
546.576

[ Exact Mass ]:
546.099121

[ PSA ]:
244.76000

[ LogP ]:
-2.84

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R42/43

[ Safety Phrases ]:
22-36/37-45-37-24

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2941905990

Customs

[ HS Code ]: 2941905990

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