1, 2-Didemethylcolchicine
Names
[ CAS No. ]:
78231-83-1
[ Name ]:
1, 2-Didemethylcolchicine
[Synonym ]:
Acetamide,N-(5,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9-oxobenzo(a)heptalen-7-yl)-,(S)
1,2-Didemethylcolchicine
Acetamide,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)
1,2-O-didemethylcolchicine
Chemical & Physical Properties
[ Density]:
1.38g/cm3
[ Boiling Point ]:
783.5ºC at 760 mmHg
[ Molecular Formula ]:
C20H21NO6
[ Molecular Weight ]:
371.38400
[ Flash Point ]:
427.6ºC
[ Exact Mass ]:
371.13700
[ PSA ]:
105.09000
[ LogP ]:
2.65650
[ Index of Refraction ]:
1.642
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC8585500
- CHEMICAL NAME :
- Acetamide, N-(5,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9- oxobenzo(a)heptalen-7 -yl)-, (S)-
- CAS REGISTRY NUMBER :
- 78231-83-1
- LAST UPDATED :
- 198912
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H21-N-O6
- MOLECULAR WEIGHT :
- 371.42
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983