R(+)-8-Hydroxy DPAT HBr

Names

[ CAS No. ]:
78095-19-9

[ Name ]:
R(+)-8-Hydroxy DPAT HBr

[Synonym ]:
C16H25NO.HBr

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₆BrNO

[ Molecular Weight ]:
328.28800

[ Exact Mass ]:
327.12000

[ PSA ]:
23.47000

[ LogP ]:
4.32960

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
22-26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.

Oncotarget 6(6) , 3932-46, (2015)

HER2-positive breast tumors are associated with a high risk of brain relapse. HER3 is thought to be an indispensible signaling substrate for HER2 (encoded by ERBB2) and is induced in breast cancer-bra...

Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats.

Behav. Brain Res. 243 , 97-101, (2013)

Antisocial aggressive behavior in adolescents represents growing clinical and social problem. Previously the implication of 5-HT1A receptor in the regulation of fear-induced aggression was shown. Here...

Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.

Neurochem. Int. 61(8) , 1344-56, (2012)

This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT...