3-(Trifluoromethyl)cinnamic acid

Names

[ CAS No. ]:
779-89-5

[ Name ]:
3-(Trifluoromethyl)cinnamic acid

[Synonym ]:
MFCD00004393
3-rifluoromethyl)CinnamicAcid
EINECS 212-301-6
2-Propenoic acid, 3-[3-(trifluoromethyl)phenyl]-
m-Trifluoromethyl cinnamic acid
3-[3-(Trifluoromethyl)phenyl]acrylic acid
RARECHEM BK HW 0018
MTF-CNA
3-(3-(Trifluoromethyl)phenyl)acrylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
289.6±35.0 °C at 760 mmHg

[ Melting Point ]:
135-137 °C(lit.)

[ Molecular Formula ]:
C₁₀H₇F₃O₂

[ Molecular Weight ]:
216.157

[ Flash Point ]:
129.0±25.9 °C

[ Exact Mass ]:
216.039810

[ PSA ]:
37.30000

[ LogP ]:
3.27

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.526

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R37/38

[ Safety Phrases ]:
S26-S37/39-S37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Practical synthesis of the calcimimetic agent, cinacalcet. Thiel OR, et al.

Tetrahedron Lett. 49(1) , 13-15, (2008)