3-Carboxy-7-hydroxycoumarin

Names

[ CAS No. ]:
779-27-1

[ Name ]:
3-Carboxy-7-hydroxycoumarin

[Synonym ]:
7-hydroxychromone-3-carboxylic acid
2H-1-Benzopyran-3-carboxylic acid, 7-hydroxy-2-oxo-
7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid
7-HYDROXYCOUMARIM-3-CARBOXYLIC ACID
RARECHEM AL BO 2319
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID FOR FLUORESCENCE
2H-1-Benzopyran-3-carboxylic acid,7-hydroxy-2-oxo
7-hydroxy-2-oxo-2H-benzopyran-3-carboxylic acid
MFCD00017491
7-hydroxy-3-carboxycoumarin
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID
UMBELLIFERONE-3-CARBOXYLIC ACID

Biological Activity

[Description]:

3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Sun WC, et al. Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3107-10.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
474.8±45.0 °C at 760 mmHg

[ Melting Point ]:
261ºC(lit.)

[ Molecular Formula ]:
C₁₀H₆O₅

[ Molecular Weight ]:
206.152

[ Flash Point ]:
198.5±22.2 °C

[ Exact Mass ]:
206.021530

[ PSA ]:
87.74000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.684

[ Water Solubility ]:
DMF: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Photoactive yellow protein-based protein labeling system with turn-on fluorescence intensity.

J. Am. Chem. Soc. 131 , 16610-16611, (2009)

Protein labeling provides significant information about protein function. In this research, we developed a novel protein labeling technique by utilizing photoactive yellow protein (PYP). PYP is a smal...

Induction of 4-hydroxycinnamate decarboxylase in Klebsiella oxytoca cells exposed to substrates and non-substrate 4-hydroxycinnamate analogs.

Biosci. Biotechnol. Biochem. 65 , 2604-2612, (2001)

The 4-hydroxycinnamate decarboxylase (4-HCD)-inducing activity of several substrate analogs toward Klebsiella oxytoca was investigated. Four E-cinnamate-class compounds, E-4-hydroxycinnamic acid (1), ...

A fluorometric assay for glycosyltransferase activities using sugars aminated and tagged with 7-hydroxycoumarin-3-carboxylic acid as substrates and high performance liquid chromatography.

Biol. Pharm. Bull. 22 , 333-338, (1999)

We developed a novel fluorometric assay method for the measurement of glycosyltransferase activities using mono- and di-saccharides aminated and tagged with 7-hydroxycoumarin-3-carboxylic acid (coumar...