DL-m-Tyrosine
Names
[ CAS No. ]:
775-06-4
[ Name ]:
DL-m-Tyrosine
[Synonym ]:
DL-m-Tyrosine;; DL-3-Tyrosine;; 3-(3-Hydroxyphenyl)-DL-alanine
DL-M-TYROSINE
EINECS 212-270-9
3-hydroxy-phenylalanine
3-Hydroxy-DL-phenylalanine
DL-3-TYROSINE
D/L-3-hydroxy-phenylalanine
3-Hydroxyphenylalanine
DL-META-TYROSINE
D,L-M-TYR
M-TYROSINE
3-(m-Hydroxyphenyl)alanine
Phenylalanine, 3-hydroxy-
2-amino-3-(3-hydroxyphenyl)propanoic acid
UNII:45KGG1D4BI
2-ammonio-3-(3-hydroxyphenyl)propanoate
DL-3-OH-Phe
MFCD00002597
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
387.2±32.0 °C at 760 mmHg
[ Melting Point ]:
280-285 °C (dec.)(lit.)
[ Molecular Formula ]:
C9H11NO3
[ Molecular Weight ]:
181.189
[ Flash Point ]:
188.0±25.1 °C
[ Exact Mass ]:
181.073898
[ PSA ]:
83.55000
[ LogP ]:
0.38
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.614
[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YP2278000
- CHEMICAL NAME :
- m-Tyrosine, DL-
- CAS REGISTRY NUMBER :
- 775-06-4
- BEILSTEIN REFERENCE NO. :
- 2416853
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H11-N-O3
- MOLECULAR WEIGHT :
- 181.21
- WISWESSER LINE NOTATION :
- QVYZ1R CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02549 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 1-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 38,251,1976
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
YP2278000
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Plant J. 63(5) , 823-35, (2010)
A large proportion of plant carbon flow passes through the shikimate pathway to phenylalanine, which serves as a precursor for numerous secondary metabolites. To identify new regulatory mechanisms aff...
Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.Cancer Res. 72(5) , 1043-50, (2012)
Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-d...
Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations.J. Clin. Endocrinol. Metab. 86(6) , 2899-902, (2001)
ABSTRACT Since glucose intake acutely increases reactive oxygen species (ROS) generation by polymorphonuclear leucocytes (PMN) and mononuclear cells (MNC), we have now investigated whether a fast over...