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Cys-Gly, oxidized

Names

[ CAS No. ]:
7729-20-6

[ Name ]:
Cys-Gly, oxidized

[Synonym ]:
N,N'-L-Cystyl-bis-glycin
L-Cystinyl-diglycin
L-Cystin-bis-(carboxymethyl-amid)
(R:R)-Bis-[2-amino-2-(carboxymethyl-carbamoyl)-aethyl]-disulfid
Cys-Gly,oxidized
((2-Amino-3-((2-amino-3-((carboxymethyl)amino)-3-oxopropyl)dithio)propanoyl)amino)acetic acid
Cys(Cys-Gly)-Gly
L-cystinyl-bis-glycine
N,N'-L-cystyl-bis-glycine
N,N'-L-Cystyl-di-glycin
(H-Cys-Gly-OH)2

Biological Activity

[Description]:

2-((R)-2-Amino-3-(((R)-2-amino-3-((carboxymethyl)amino)-3-oxopropyl)disulfanyl)propanamido)acetic acid is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.535g/cm3

[ Boiling Point ]:
788.5ºC at 760mmHg

[ Molecular Formula ]:
C10H18N4O6S2

[ Molecular Weight ]:
354.40300

[ Flash Point ]:
430.7ºC

[ Exact Mass ]:
354.06700

[ PSA ]:
235.44000

[ Index of Refraction ]:
1.626

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Synthetic Route

Articles

Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients.

Mov. Disord 26 , 543-546, (2011)

Oxidative stress is influenced by the thiol homeostasis, which determines the redox milieu. One of its components is Cysteinyl-glycine (Cys-Gly) generation, as its metabolic precursor is the free radi...

Dug1p Is a Cys-Gly peptidase of the gamma-glutamyl cycle of Saccharomyces cerevisiae and represents a novel family of Cys-Gly peptidases.

J. Biol. Chem. 284 , 14493-14502, (2009)

GSH metabolism in yeast is carried out by the gamma-glutamyl cycle as well as by the DUG complex. One of the last steps in the gamma-glutamyl cycle is the cleavage of Cys-Gly by a peptidase to the con...

From cysteine to longer chain thiols: thermodynamic analysis of cadmium binding by phytochelatins and their fragments.

Metallomics 3 , 838-846, (2011)

Isothermal Titration Calorimetry (ITC) was used to study the binding of Cd(2+) by phytochelatins ((γGlu-Cys)(n)-Gly, PC(n); n = 1-5) and their selected fragments (Cys, Cys-Gly and γGlu-Cys) in order t...


More Articles


Related Compounds

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