Carboxyatractyloside

Names

[ Name ]:
Carboxyatractyloside

[Synonym ]:
(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid tripotassium salt
(2β,13α,15α)-15-Hydroxy-2-{[2-O-(3-methylbutanoyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy}kaur-16-ene-18,19-dioic acid
Carboxyatractyloside potassium salt
Carboxyatractyloside

Biological Activity

[Description]:

Carboxyatractyloside is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Pebay-Peyroula E, et al. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature. 2003 Nov 6;426(6962):39-44.

Chemical & Physical Properties

[ Density]:
1.58±0.1 g/cm3

[ Molecular Formula ]:
C₃₁H₄₃K₃O₁₈S₂

[ Molecular Weight ]:
770.816

[ Exact Mass ]:
770.212585

[ PSA ]:
312.27000

[ LogP ]:
3.16

[ Index of Refraction ]:
1.621

[ Storage condition ]:
2-8℃

[ Water Solubility ]:
Insuluble (5.5E-3 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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