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SAP-I

Names

[ CAS No. ]:
76901-59-2

[ Name ]:
SAP-I

[Synonym ]:
Speract

Biological Activity

[Description]:

Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism
Research Areas >> Metabolic Disease
Peptides

[In Vitro]

Speract is a decapeptide from the outer jelly layer of theStrongylocentrotus purpuratus egg that upon binding to its receptor in the sperm, stimulates sperm motility, respiration and ion fluxes, among other physiological events. Speract increases NADH levels and depolarizes the sea urchin sperm mitochondrion[1].

[References]

[1]. García-Rincón J, et al. Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism. Biochim Biophys Acta. 2016 Apr;1857(4):415-26.


[Related Small Molecules]

Rotenone | FCCP | Elamipretide | NIM811 | Daidzin | TRO 19622 | Imeglimin hydrochloride | α-Lipoic Acid | Mitochonic acid 5 | ER-000444793 | Mito-TEMPO | lipoic acid | Adjudin | Thiabendazole | Asp-AMS

Chemical & Physical Properties

[ Density]:
1.337g/cm3

[ Boiling Point ]:
1502.321ºC at 760 mmHg

[ Molecular Formula ]:
C38H57N11O14

[ Molecular Weight ]:
891.92400

[ Flash Point ]:
862.373ºC

[ Exact Mass ]:
891.40900

[ PSA ]:
405.61000

[ Index of Refraction ]:
1.565

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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