Boc-Cys(NPys)-OH

Names

[ Name ]:
Boc-Cys(NPys)-OH

[Synonym ]:
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-[(3-nitro-2-pyridinyl)disulfanyl]-L-alanine
n-(tert-butoxycarbonyl)-3-[(3-nitropyridin-2-yl)disulfanyl]-l-alanine
Boc-Cys-S-(3-nitro-2-pyridinesulfenyl)
Boc-cys(npys)
N-t-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine
t-Bcnp
Boc-cys(npys)-OH
MFCD00153301
L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-3-[(3-nitro-2-pyridinyl)dithio]-
Nalpha-Boc-S-(3-nitro-2-pyridylthio)-L-cysteine

Biological Activity

[Description]:

Boc-Cys(Npys)-OH is a cysteine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
553.9±50.0 °C at 760 mmHg

[ Melting Point ]:
-160ºC (dec.)

[ Molecular Formula ]:
C₁₃H₁₇N₃O₆S₂

[ Molecular Weight ]:
375.421

[ Flash Point ]:
288.8±30.1 °C

[ Exact Mass ]:
375.055878

[ PSA ]:
184.94000

[ LogP ]:
4.25

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.616

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Controlled peptide-protein conjugation by means of 3-nitro-2-pyridinesulfenyl protection-activation.

Int. J. Pept. Protein Res. 32(3) , 161-6, (1988)

The disulfide bond in S-3-nitro-2-pyridinesulfenyl (S-Npys) compounds is stable towards the acid treatment used in solid-phase peptide synthesis, yet the liability of S-Npys-peptides towards nucleophi...

Preparation of Boc-[S-(3-nitro-2-pyridinesulfenyl)]-cysteine and its use for unsymmetrical disulfide bond formation.

Int. J. Pept. Protein Res. 28(2) , 107-12, (1986)

The 3-nitro-2-pyridinesulfenyl (Npys) derivative of cysteine was prepared and used to facilitate the formation of an unsymmetrical disulfide bond. Since this derivative is stable in trifluoroacetic ac...

Effects of sulfhydryl-modifying reagents, 3-nitro-2-pyridinesulfenyl compounds, on the coupling between inhibitory receptors and GTP-binding proteins Gi/Go in rat brain membranes.

Mol. Pharmacol. 38(2) , 184-91, (1990)

To gain insight into the coupling mechanism of inhibitory receptors, 5-hydroxytryptamine1A receptors and alpha 2-adrenoceptors, with GTP-binding proteins (G proteins) in the central nervous system, we...