Ronidazole
Names
[ CAS No. ]:
7681-76-7
[ Name ]:
Ronidazole
[Synonym ]:
(1-Methyl-5-nitro-1H-imidazol-2-yl)methyl carbamate
Ridazole
Carbamic Acid (1-Methyl-5-nitroimidazol-2-yl)methyl Ester
Ridzol P
Dugro
(1-Methyl-5-nitroimidazole-2-yl)methyl Carbamate
2-Carbamoyloxymethyl-1-methyl-5-nitro-imidazol
1-Methyl-2-[(carbamoyloxy)methyl]-5-nitroimidazole
Ridzol
1-Methyl-5-nitroimidazole-2-methanol Carbamate (Ester)
1H-Imidazole-2-methanol, 1-methyl-5-nitro-, carbamate (ester)
MCMN
2-carbamoyloxymethyl-1-methyl-5-nitro-1H-imidazole
Ronidazole
Ronidazol
EINECS 231-675-1
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
502.3±30.0 °C at 760 mmHg
[ Melting Point ]:
167-169°
[ Molecular Formula ]:
C6H8N4O4
[ Molecular Weight ]:
200.152
[ Flash Point ]:
257.6±24.6 °C
[ Exact Mass ]:
200.054550
[ PSA ]:
115.96000
[ LogP ]:
-0.45
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.651
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NI6803000
- CHEMICAL NAME :
- Imidazole-2-methanol, 1-methyl-5-nitro-, carbamate (ester)
- CAS REGISTRY NUMBER :
- 7681-76-7
- BEILSTEIN REFERENCE NO. :
- 0886221
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C6-H8-N4-O4
- MOLECULAR WEIGHT :
- 200.18
- WISWESSER LINE NOTATION :
- T5N CNJ A1 B1OVZ ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,289,1976
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
NI6803000
[ HS Code ]:
2933290090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 960 , 105-15, (2014)
An UHPLC-MS/MS method was developed for the quantitative confirmatory analysis of residues of nitroimidazole drugs (dimetridazole, ipronidazole, metronidazole, ornidazole and ronidazole) and their cor...
Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry.J. AOAC Int. 97(6) , 1538-45, (2015)
A sensitive and reliable analytical method based on HPLC/MSIMS has been developed for the simultaneous determination of 15 nitroimidazoles in cosmetics. A diversity of cosmetic samples, including powd...
Tritrichomonas foetus infection in cats with diarrhoea in a rescue colony in Italy.J. Feline Med. Surg. 11(2) , 131-4, (2009)
Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smear...