5-Brom-2-fluorpyridin

[Description]:

[Related Catalog]:

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
178.0±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₃BrFN

[ Molecular Weight ]:
175.99

[ Flash Point ]:
61.4±21.8 °C

[ Exact Mass ]:
174.943283

[ PSA ]:
12.89000

[ LogP ]:
1.80

[ Vapour Pressure ]:
1.4±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.534

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ HS Code ]:
2933399090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Versatile synthesis of 3,5-disubstituted 2-fluoropyridines and 2-pyridones.

J. Org. Chem. 68(8) , 3352-5, (2003)

5-bromo-2-fluoro-3-pyridylboronic acid (3) was prepared in high yield by ortho-lithiation of 5-bromo-2-fluoropyridine (1), followed by reaction with trimethylborate. Suzuki reaction of 3 with a range ...

Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165.

J. Org. Chem. 68(6) , 2475-8, (2003)

Two racemic fluoropyridine analogues 4 and 5 of the potent nicotinic agonist UB-165 have been synthesized. Halogenated pyridines 7 and 12 provided the organometallic reagents needed for the Negishi an...

Aromatic fluorine compounds. XI. Replacement of chlorine by fluorine in halopyridines. Finger GC, et al.

J. Org. Chem. 28(6) , 1666-1668, (1963)

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