Yuanhuadin

Names

[ Name ]:
Yuanhuadin

Biological Activity

[Description]:

Yuanhuadin, extracted from Genkwa Flos Daphne genkwa, has antitumor activity through inhibiting Akt/mTOR and EGFR pathways, induce cell-cycle arrest and abortion[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

Signaling Pathways >> PI3K/Akt/mTOR >> Akt

Research Areas >> Inflammation/Immunology

[References]

[1]. Christian Bailly, et al. Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview. Biomolecules. 2022 Feb; 12(2): 192.

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
704.4ºC at 760 mmHg

[ Molecular Formula ]:
C₃₂H₄₂O₁₀

[ Molecular Weight ]:
586.67000

[ Flash Point ]:
222.4ºC

[ Exact Mass ]:
586.27800

[ PSA ]:
144.28000

[ LogP ]:
2.41050

[ Index of Refraction ]:
1.607

[ Storage condition ]:
2-8°C

Related Compounds

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